Marlene M. Rayner
Wilmington University(US)
Publications by Year
Research Areas
HIV/AIDS drug development and treatment, HIV Research and Treatment, Click Chemistry and Applications, Biochemical and Molecular Research, HIV/AIDS Research and Interventions
Most-Cited Works
- → Rational Design of Potent, Bioavailable, Nonpeptide Cyclic Ureas as HIV Protease Inhibitors(1994)835 cited
- → Cyclic HIV Protease Inhibitors: Synthesis, Conformational Analysis, P2/P2‘ Structure−Activity Relationship, and Molecular Recognition of Cyclic Ureas(1996)170 cited
- → Improved cyclic urea inhibitors of the HIV-1 protease: synthesis, potency, resistance profile, human pharmacokinetics and X-ray crystal structure of DMP 450(1996)148 cited
- → Preparation and Structure−Activity Relationship of Novel P1/P1‘-Substituted Cyclic Urea-Based Human Immunodeficiency Virus Type-1 Protease Inhibitors(1996)106 cited
- → Potent cyclic urea HIV protease inhibitors with benzofused heterocycles as P2/P2′ groups(1996)102 cited
- → Selection conditions affect the evolution of specific mutations in the reverse transcriptase gene associated with resistance to DMP 266(1996)54 cited
- → Determinants of the human immunodeficiency virus type 1 p15NC-RNA interaction that affect enhanced cleavage by the viral protease(1997)51 cited
- → Nonpeptide Cyclic Cyanoguanidines as HIV-1 Protease Inhibitors: Synthesis, Structure−Activity Relationships, and X-ray Crystal Structure Studies(1998)50 cited
- → DPC 817: a Cytidine Nucleoside Analog with Activity against Zidovudine- and Lamivudine-Resistant Viral Variants(2002)48 cited
- → Design, Synthesis, and Evaluation of Tetrahydropyrimidinones as an Example of a General Approach to Nonpeptide HIV Protease Inhibitors(1997)46 cited