Nickolay Y. Chirgadze
Ontario Institute for Cancer Research(CA)University Health Network(CA)Princess Margaret Cancer Centre(CA)Xanadu Quantum Technologies (Canada)(CA)
Publications by Year
Research Areas
Enzyme Structure and Function, Chemical Synthesis and Analysis, Protein Kinase Regulation and GTPase Signaling, RNA and protein synthesis mechanisms, Blood Coagulation and Thrombosis Mechanisms
Most-Cited Works
- → Viracept (Nelfinavir Mesylate, AG1343): A Potent, Orally Bioavailable Inhibitor of HIV-1 Protease(1997)619 cited
- → Structure-based design of the first potent and selective inhibitor of human non-pancreatic secretory phospholipase A2(1995)214 cited
- → Structure of the Shigella T3SS effector IpaH defines a new class of E3 ubiquitin ligases(2008)158 cited
- → A second binding site for hydroxytamoxifen within the coactivator-binding groove of estrogen receptor β(2006)110 cited
- → Crystal Structure of Human Parathyroid Hormone 1–34 at 0.9-Å Resolution(2000)109 cited
- → The Discovery of Polo-Like Kinase 4 Inhibitors: Design and Optimization of Spiro[cyclopropane-1,3′[3H]indol]-2′(1′H)-ones as Orally Bioavailable Antitumor Agents(2014)109 cited