Wan Yun Ho
National University of Singapore(SG)Duke-NUS Medical School(SG)
Publications by Year
Research Areas
Amyotrophic Lateral Sclerosis Research, Parkinson's Disease Mechanisms and Treatments, Autophagy in Disease and Therapy, Alzheimer's disease research and treatments, Neurogenetic and Muscular Disorders Research
Most-Cited Works
- → Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis(2019)90 cited
- → Cell-autonomous requirement of TDP-43, an ALS/FTD signature protein, for oligodendrocyte survival and myelination(2018)88 cited
- → Loss of TDP-43 in astrocytes leads to motor deficits by triggering A1-like reactive phenotype and triglial dysfunction(2020)74 cited
- → The ALS-FTD-linked gene product, C9orf72, regulates neuronal morphogenesis via autophagy(2019)69 cited
- → C9orf72 intermediate repeats are associated with corticobasal degeneration, increased C9orf72 expression and disruption of autophagy(2019)60 cited
- → TDP-43 mediates SREBF2-regulated gene expression required for oligodendrocyte myelination(2021)50 cited
- → Central nervous system cholesterol metabolism in health and disease(2022)48 cited
- → Cholesterol dyshomeostasis in amyotrophic lateral sclerosis: cause, consequence, or epiphenomenon?(2021)42 cited
- → Dysfunction in nonsense-mediated decay, protein homeostasis, mitochondrial function, and brain connectivity in ALS-FUS mice with cognitive deficits(2021)28 cited
- → Deregulated expression of a longevity gene, Klotho, in the C9orf72 deletion mice with impaired synaptic plasticity and adult hippocampal neurogenesis(2020)23 cited