LJ Fairbairn
Stellenbosch University(ZA)
Publications by Year
Research Areas
Virus-based gene therapy research, DNA Repair Mechanisms, RNA Interference and Gene Delivery, Acute Myeloid Leukemia Research, Carcinogens and Genotoxicity Assessment
Most-Cited Works
- → Suppression of apoptosis allows differentiation and development of a multipotent hemopoietic cell line in the absence of added growth factors(1993)373 cited
- → CD34+AC133+Cells Isolated from Cord Blood are Highly Enriched in Long‐Term Culture‐Initiating Cells, NOD/SCID‐Repopulating Cells and Dendritic Cell Progenitors(1998)210 cited
- → Genotoxicity studies on the azo dye Direct Red 2 using the in vivo mouse bone marrow micronucleus test(1999)68 cited
- → Human monocytes expressing a CEA-specific chimeric CD64 receptor specifically target CEA-expressing tumour cells in vitro and in vivo(2006)63 cited
- → Long-term in vitro correction of alpha-L-iduronidase deficiency (Hurler syndrome) in human bone marrow.(1996)50 cited
- → Chemoprotective gene transfer II: multilineage in vivo protection of haemopoiesis against the effects of an antitumour agent by expression of a mutant human O6-alkylguanine-DNA alkyltransferase(1998)46 cited
- → Long-term protection of hematopoiesis against the cytotoxic effects of multiple doses of nitrosourea by retrovirus-mediated expression of human O6-alkylguanine-DNA-alkyltransferase(1996)45 cited
- → Chemoprotective gene transfer I: transduction of human haemopoietic progenitors with O6-benzylguanine-resistant O6-alkylguanine-DNA alkyltransferase attenuates the toxic effects of O6-alkylating agents in vitro(1998)34 cited
- → Chemoprotection of normal tissues by transfer of drug resistance genes(1996)34 cited
- → A novel dual function retrovirus expressing multidrug resistance 1 and O6-alkylguanine-DNA-alkyltransferase for engineering resistance of haemopoietic progenitor cells to multiple chemotherapeutic agents(1999)31 cited