Glynn Faircloth
PharmaMar (Spain)(ES)
Publications by Year
Research Areas
Marine Sponges and Natural Products, Synthesis and Biological Activity, Synthesis and biological activity, Synthesis and Characterization of Heterocyclic Compounds, Microbial Natural Products and Biosynthesis
Most-Cited Works
- → Ecteinascidin-743 (ET-743), a natural marine compound, with a unique mechanism of action(2001)256 cited
- → Ecteinascidin 743, a transcription-targeted chemotherapeutic that inhibits MDR1 activation(2000)206 cited
- → Interference of transcriptional activation by the antineoplastic drug ecteinascidin-743(2000)195 cited
- → New Marine Derived Anticancer Therapeutics ─ A Journey from the Sea to Clinical Trials(2004)178 cited
- → Unique pattern of ET-743 activity in different cellular systems with defined deficiencies in DNA-repair pathways(2001)160 cited
- → Structure−Activity Relationships of the Didemnins(1996)151 cited
- → The marine compound spisulosine, an inhibitor of cell proliferation, promotes the disassembly of actin stress fibers(2000)146 cited
- → Aplidine, a new anticancer agent of marine origin, inhibits vascular endothelial growth factor (VEGF) secretion and blocks VEGF-VEGFR-1 (flt-1) autocrine loop in human leukemia cells MOLT-4(2003)143 cited
- → In vitro antitumor activity of the novel marine agent, Ecteinascidin-743 (ET-743, NSC-648766) against human tumors explanted from patients(1998)135 cited
- Ecteinascidin-743, a new marine natural product with potent antitumor activity on human ovarian carcinoma xenografts.(1998)