Giuseppina De Simone
Azienda di Rilievo Nazionale ed Alta Specializzazione(IT)
Publications by Year
Research Areas
Enzyme function and inhibition, Synthesis and Catalytic Reactions, Cholinesterase and Neurodegenerative Diseases, Chemical Reactions and Mechanisms, Phenothiazines and Benzothiazines Synthesis and Activities
Most-Cited Works
- → Multiple Binding Modes of Inhibitors to Carbonic Anhydrases: How to Design Specific Drugs Targeting 15 Different Isoforms?(2012)1,195 cited
- → Crystal structure of the catalytic domain of the tumor-associated human carbonic anhydrase IX(2009)514 cited
- → Histone deacetylase and Cullin3–RENKCTD11 ubiquitin ligase interplay regulates Hedgehog signalling through Gli acetylation(2010)323 cited
- → Biochemical Characterization of CA IX, One of the Most Active Carbonic Anhydrase Isozymes(2008)303 cited
- → Anticancer carbonic anhydrase inhibitors: a patent review (2008 – 2013)(2013)263 cited
- → Exploiting the hydrophobic and hydrophilic binding sites for designing carbonic anhydrase inhibitors(2013)251 cited