Leonard Guarente
IIT@MIT(US)Lifespan(US)Elysium Therapeutics (United States)(US)Massachusetts Institute of Technology(US)
Publications by Year
Research Areas
Sirtuins and Resveratrol in Medicine, Adipose Tissue and Metabolism, Genetics, Aging, and Longevity in Model Organisms, Fungal and yeast genetics research, Autophagy in Disease and Therapy
Most-Cited Works
- → Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase(2000)3,467 cited
- → hSIR2SIRT1 Functions as an NAD-Dependent p53 Deacetylase(2001)2,632 cited
- → The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms(1999)2,256 cited
- → Negative Control of p53 by Sir2α Promotes Cell Survival under Stress(2001)2,065 cited
- → Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-γ(2004)1,940 cited
- → Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans(2001)1,906 cited