Guanghui Tian
China Energy Engineering Corporation (China)(CN)Hainan General Hospital(CN)Affiliated Hospital of Youjiang Medical University for Nationalities(CN)Hainan Medical College Hospital(CN)Viva Biotech (China)(CN)Hainan Medical University(CN)
Publications by Year
Research Areas
Phosphodiesterase function and regulation, Pharmacological Receptor Mechanisms and Effects, Phenothiazines and Benzothiazines Synthesis and Activities, SARS-CoV-2 and COVID-19 Research, Advanced biosensing and bioanalysis techniques
Most-Cited Works
- → Structural basis for inhibition of the RNA-dependent RNA polymerase from SARS-CoV-2 by remdesivir(2020)1,283 cited
- → Structural Basis for the Inhibition of the RNA-Dependent RNA Polymerase from SARS-CoV-2 by Remdesivir(2020)138 cited
- → Design and development of an oral remdesivir derivative VV116 against SARS-CoV-2(2021)125 cited
- → Utilization of Halogen Bond in Lead Optimization: A Case Study of Rational Design of Potent Phosphodiesterase Type 5 (PDE5) Inhibitors(2011)121 cited
- → Pharmacokinetics-Driven Optimization of 4(3H)-Pyrimidinones as Phosphodiesterase Type 5 Inhibitors Leading to TPN171, a Clinical Candidate for the Treatment of Pulmonary Arterial Hypertension(2019)37 cited
- → Design, Synthesis, and Pharmacological Evaluation of Monocyclic Pyrimidinones as Novel Inhibitors of PDE5(2012)36 cited