Why the missing heritability might not be in the DNA
BioEssays2017Vol. 39(7)
Citations Over TimeTop 10% of 2017 papers
Abstract
There are four major hypotheses (H1, H2, H3, and H4) as to the source of missing heritability. We propose that estimates obtained from GWAS underestimate heritability by not taking into account non-DNA (epigenetic) sources of heritability. Taking those factors into account (H4) should result in increased heritability estimates.
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