Downregulation of microRNA‐6125 promotes colorectal cancer growth through YTHDF2‐dependent recognition of N6‐methyladenosine‐modified GSK3β
Clinical and Translational Medicine2021Vol. 11(10), pp. e602–e602
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Hongyan Li, Ning Zhang, Xueli Jiao, Cong Wang, Wenhao Sun, Yanyu He, Ganglin Ren, Shirui Huang, Mengjie Li, Yi-Xin Chang, Zihui Jin, Qipeng Xie, Xiaodong Zhang, Haishan Huang, Honglei Jin
Abstract
MiR-6125 regulates YTHDF2 and thus plays a critical role in regulating the Wnt/β-catenin pathway, thereby affecting the growth of CRC. Collectively, these results suggest that miR-6125 and YTHDF2 are potential targets for treatment of CRC.
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