Evaluation of 2,3,7,8 Specific Congener and Toxic Potency of Persistent Polychlorinated Dibenzo-p-Dioxins and Polychlorinated Dibenzofurans in Cetaceans from the Mediterranean Sea, Italy

Citations Over TimeTop 19% of 2000 papers

Abstract

The present study investigates individual 2,3,7,8-substituted polychlorinated dibenzo-p-dioxin (PCDD) and polychlorinated dibenzofuran (PCDF) concentrations in cetaceans and assesses the PCDD and PCDF contributions to the total TCDD equivalent concentration. Liver samples of a variety of cetaceans species found stranded along the Italian coasts during the period of 1987−1992 were analyzed for PCDDs and PCDFs. The main aims were to scrutinize levels and patterns of PCDDs and PCDFs for the first time in cetaceans from the Mediterranean Sea and to estimate whether chlorinated compounds mentioned are implicated in the exceptionally high mortality of dolphins that occurred in the Mediterranean Sea during 1990−1992. PCDD and PCDF profiles were dominated by congeners OCCD and OCDF. The new toxic equivalency factors recommended by WHO in 1997 were used for calculation of dioxin-like toxicity. On the basis of our previous study of PCBs, the overall TEQ calculated from the 2,3,7,8-substituted PCDDs and PCDFs do not contribute as much dioxin-like toxicity as PCBs.

Related Papers

• → Pilot study (Phase II) for determining polychlorinated dibenzo-p-dioxin (PCDD) and polychlorinated dibenzofuran (PCDF) levels in serum of Seveso, Italy residents collected at the time of exposure: Future plans(1990)33 cited
• → Evaluation of 2,3,7,8 Specific Congener and Toxic Potency of Persistent Polychlorinated Dibenzo-p-Dioxins and Polychlorinated Dibenzofurans in Cetaceans from the Mediterranean Sea, Italy(2000)28 cited
• → Tissue concentrations and induction of a hepatic monooxygenase in male Wistar rats after repeated doses of defined polychlorinated dibenzo-p-dioxin and dibenzofuran (PCDDs and PCDFs) mixtures(2001)12 cited
• → Polychlorinated dibenzo-p-dioxins and dibenzofurans levels in persons with high and normal levels of 2,3,7,8-tetrachlorodibenzo-p-dioxin(1987)11 cited
• Detection of Polychlorinated Dibenzo-p-dioxins and Polychlorinated Dibenzofurans in Some Environmental Samples from the Palestinian Territories (Research Note)(2010)