Gold-Catalyzed Deoxygenated Cyclization of cis-2,4-Dien-1-als with Regioselective Addition of Two Nucleophiles. One-Pot Synthesis of Highly Functionalized Cyclopentene Framework

Citations Over TimeTop 10% of 2007 papers

Abstract

We report a new gold-catalyzed deoxygenated cyclization of cis-2,4-dien-1-als with external nucleophiles at ambient temperatures, which leads to a 1,4-double nucleophilic addition to the newly formed cyclopentene ring. The use of this cyclization is reflected not only by its compatibility with a wide scope of nucleophiles, but also by a facile construction of complex frameworks in diversified approaches.

Related Papers

• → Gold-Catalyzed Deoxygenated Cyclization of cis-2,4-Dien-1-als with Regioselective Addition of Two Nucleophiles. One-Pot Synthesis of Highly Functionalized Cyclopentene Framework(2007)73 cited
• → Comprehensive Theoretical Investigation on the Regioselectivity in the Nucleophilic Ring Opening of Epoxides(2013)13 cited
• → Azetidiniums: Ring‐Expansion to Pyrrolidines, Piperidines, Azepanes, and Azocanes(2020)16 cited
• → Nucleophilic alkenoylation of aldehydes with metalated α-aminonitriles: regioselective synthesis of α-hydroxyenones(1999)20 cited
• → ESI-IMS-QTOF: a regioselective Michael addition study(2013)