DNA Sensing by Field-Effect Transistors Based on Networks of Carbon Nanotubes
Journal of the American Chemical Society2007Vol. 129(46), pp. 14427–14432
Citations Over TimeTop 10% of 2007 papers
Ee Ling Gui, Lain‐Jong Li, Keke Zhang, Yangping Xu, Xiaochen Dong, Xinning Ho, Pooi See Lee, Johnson Kasim, Zexiang Shen, John A. Rogers, Subodh G. Mhaisalkar
Abstract
We report on the sensing mechanism of electrical detection of deoxyribonucleic acid (DNA) hybridization for Au- and Cr-contacted field effect transistors based on single-walled carbon nanotube (SWCNT) networks. Barrier height extraction via low-temperature electrical measurement provides direct evidence for the notion that the energy level alignment between electrode and SWCNTs can be affected by DNA immobilization and hybridization. The study of location-selective capping using photoresist provides comprehensive evidence that the sensing of DNA is dominated by the change in metal-SWCNT junctions rather than the channel conductance.
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