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Ivermectin, a new broad-spectrum antiparasitic agent
Journal of Medicinal Chemistry1980Vol. 23(10), pp. 1134–1136
Citations Over TimeTop 1% of 1980 papers
John C. Chabala, Helmut Mrozik, Richard L. Tolman, Philip Eskola, A Lusi, Louis H. Peterson, Mary F. Woods, Michael H. Fisher, William C. Campbell
Abstract
22,23-Dihydroavermectin B1, ivermectin, derived from avermectin B1 by selective hydrogenation using Wilkinson's homogenous catalyst [Ph3P)3RhCl], was shown to be a highly effective drug for the treatment of a wide variety of metazoan parasitic diseases in animals.
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