7-Alkoxy-4-phenylamino-3-quinolinecar-bonitriles as Dual Inhibitors of Src and Abl Kinases
Journal of Medicinal Chemistry2004Vol. 47(7), pp. 1599–1601
Citations Over TimeTop 10% of 2004 papers
Diane H. Boschelli, Yanong D. Wang, S.A. Johnson, Biqi Wu, Fei Ye, Ana Carolina Barrios Sosa, Jennifer M. Golas, Frank Boschelli
Abstract
We previously reported that several 7-alkoxy-4-phenylamino-3-quinolinecarbonitriles were potent inhibitors of Src kinase activity. We disclose here a new highly efficient and versatile route to these compounds, which are also potent inhibitors of Abl kinase.
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