PI3Kδ and PI3Kγ as Targets for Autoimmune and Inflammatory Diseases

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Abstract

ADVERTISEMENT RETURN TO ISSUEPerspectiveNEXTPI3Kδ and PI3Kγ as Targets for Autoimmune and Inflammatory DiseasesTimothy D. Cushing*†, Daniela P. Metz‡, Douglas A. Whittington§, and Lawrence R. McGee†View Author Information† Therapeutic Discovery, Amgen Inc., 1120 Veterans Boulevard, South San Francisco, California 94080, United States‡ Inflammation Research, Amgen Inc., One Amgen Center Drive, Thousand Oaks, California 91320, United States§ Molecular Structure and Characterization, Amgen Inc., 360 Binney Street, Cambridge, Massachusetts 02142, United States*Phone: 1-650-224-2406. E-mail: [email protected]Cite this: J. Med. Chem. 2012, 55, 20, 8559–8581Publication Date (Web):August 27, 2012Publication History Received15 June 2012Published online13 September 2012Published inissue 25 October 2012https://pubs.acs.org/doi/10.1021/jm300847whttps://doi.org/10.1021/jm300847wreview-articleACS PublicationsCopyright © 2012 American Chemical SocietyRequest reuse permissionsArticle Views4317Altmetric-Citations75LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Inflammation,Inhibitors,Peptides and proteins,Rodent models,Selectivity Get e-Alerts

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