Selective Catalytic Hydrogenation of Nitro Groups in the Presence of Activated Heteroaryl Halides
The Journal of Organic Chemistry2011Vol. 76(23), pp. 9841–9844
Citations Over Time
Abstract
Chemoselective reduction of nitro groups in the presence of activated heteroaryl halides was achieved via catalytic hydrogenation with a commercially available sulfided platinum catalyst. The optimized conditions employ low temperature, pressure, and catalyst loading (<0.1 mol % Pt) to afford heteroaromatic amines with minimal hydrodehalogenation byproducts.
Related Papers
- → Molecular Structure of Nitro- and Nitrito-Copper Complexes as Reaction Intermediates in Electrochemical Reduction of Nitrite to Dinitrogen Oxide(1995)68 cited
- → Selective Catalytic Hydrogenation of Nitro Groups in the Presence of Activated Heteroaryl Halides(2011)40 cited
- → The Synthetic Reactions of Aliphatic Nitro Compounds. VII. The Synthesis of α-Amino Acids from the Nitroacetic Ester(1973)21 cited
- → Carbonylation of aromatic nitro compounds to isocyanates using a homogeneous trans-Pd(Py)2Cl2 complex catalyst: IR spectroscopic study and reaction mechanism(1986)17 cited
- Advances in Catalytic Reduction of Aromatic Nitro Compounds to Aromatic Amines Using CO/H_2O(2003)