A Practical Synthesis of Nelfinavir, an HIV-Protease Inhibitor, Using a Novel Chiral C4 Building Block: (5R,6S)-2,2-Dimethyl-5-hydroxy-1,3-dioxepan-6-ylammonium Acetate

Citations Over TimeTop 14% of 1998 papers

Abstract

ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTA Practical Synthesis of Nelfinavir, an HIV-Protease Inhibitor, Using a Novel Chiral C4 Building Block: (5R,6S)-2,2-Dimethyl-5-hydroxy-1,3-dioxepan-6-ylammonium AcetateTakashi Inaba, Angela G. Birchler, Yasuki Yamada, Shoichi Sagawa, Katsuyuki Yokota, Koji Ando, and Itsuo UchidaView Author Information Central Pharmaceutical Research Institute, Japan Tobacco, Inc., 1-1, Murasaki-cho Takatsuki Osaka, 569-1125, Japan, and Agouron Pharmaceuticals, Inc., 3565 General Atomics Court, San Diego, California 92121 Cite this: J. Org. Chem. 1998, 63, 22, 7582–7583Publication Date (Web):October 10, 1998Publication History Received28 July 1998Published online10 October 1998Published inissue 1 October 1998https://doi.org/10.1021/jo981472nCopyright © 1998 American Chemical SocietyRIGHTS & PERMISSIONSArticle Views1126Altmetric-Citations33LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit Read OnlinePDF (35 KB) Get e-AlertsSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Alcohols,Ethers,Hydroxyls,Ring opening reactions,Solvents Get e-Alerts

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