Shoichi Sagawa
Japan Tobacco (Japan)(JP)
Publications by Year
Research Areas
Asymmetric Synthesis and Catalysis, HIV/AIDS drug development and treatment, HIV Research and Treatment, Receptor Mechanisms and Signaling, Oxidative Organic Chemistry Reactions
Most-Cited Works
- → Catalytic Asymmetric Aminolysis of 3,5,8-Trioxabicyclo[5.1.0]octane Providing an Optically Pure 2-Amino-1,3,4-butanetriol Equivalent(1999)139 cited
- → Synthesis of anilino-monoindolylmaleimides as potent and selective PKCβ inhibitors(2004)61 cited
- → (1S)-1-[(4R)-2,2-Dimethyl-1,3-dioxolan-4-yl]-2-hydroxyethylammonium Benzoate, A Versatile Building Block for Chiral 2-Aminoalkanols: Concise Synthesis and Application to Nelfinavir, a Potent HIV-Protease Inhibitor(2000)48 cited
- → Synthesis, SAR studies, and pharmacological evaluation of 3-anilino-4-(3-indolyl) maleimides with conformationally restricted structure as orally bioavailable PKCβ-selective inhibitors(2006)44 cited
- → Novel protein kinase C‐β isoform selective inhibitor JTT‐010 ameliorates both hyper‐ and hypoalgesia in streptozotocin‐ induced diabetic rats(2004)42 cited
- → A Practical Synthesis of Nelfinavir, an HIV-Protease Inhibitor, Using a Novel Chiral C4 Building Block: (5R,6S)-2,2-Dimethyl-5-hydroxy-1,3-dioxepan-6-ylammonium Acetate(1998)39 cited
- → Discovery of pyrrolopyridazines as novel DGAT1 inhibitors(2010)31 cited
- → Discovery of 6-Phenylpyrimido[4,5-b][1,4]oxazines as Potent and Selective Acyl CoA:Diacylglycerol Acyltransferase 1 (DGAT1) Inhibitors with in Vivo Efficacy in Rodents(2014)30 cited
- → Synthesis of Anilino‐monoindolylmaleimides as Potent and Selective PKCβ Inhibitors.(2005)21 cited
- → Efficient synthesis of enantiomerically pure 5,5-Dimethyl-4-hydroxy-2-cyclopentenone(1995)20 cited