%Rigidone, a Sesquiterpeneo-Quinone from the GorgonianPseudopterogorgia rigida
Journal of Natural Products1997Vol. 60(3), pp. 309–311
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Abstract
As part of a search for novel biologically active compounds in the Macrophage Scavenger Receptor (MSR) assay, the EtOAc extract of a gorgonian coral, Pseudopterogorgia rigida, was shown to be active. Bioassay-guided fractionation of the extract yielded curcuphenol, curcuhydroquinone, curcuquinone, and a novel o-quinone, rigidone (1). The structure and stereochemistry of 1 was determined by interpretation of spectral data and chemical transformation.
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