Synthesis of Enantiopure α,α-Disubstituted Amino Acids from the Asymmetric Strecker Reaction Products of Aldehydes
Organic Letters2000Vol. 2(16), pp. 2515–2517
Citations Over TimeTop 10% of 2000 papers
Abstract
Treatment of the enolates of 4 generated from the asymmetric Strecker reaction products with alkyl halides or aldehydes provided the corresponding functionalized products with high diastereoselectivity. Deprotection of these products afforded the corresponding enantiopure alpha,alpha-dialkyl amino acids.
Related Papers
- → Asymmetric strecker synthesis using enantiopure sulfinimines: A convenient synthesis of α-amino acids(1994)67 cited
- → Halogen exchange reactions between alkyl halides and aqueous hydrogen halides. A new method for preparation of alkyl halides.(1990)29 cited
- → Synthesis of Enantiopure α,α-Disubstituted Amino Acids from the Asymmetric Strecker Reaction Products of Aldehydes(2000)28 cited
- → Reaction of alkyl halides with dialkyltins(1967)12 cited
- → The Use of S-Alkyl-N-Phenylthiuronium Picrates, Styphnates and Picrolonates for the Characterisation of Alkyl Halides(1960)2 cited