The Application of Chiral Aminonaphthols in the Enantioselective Addition of Diethylzinc to Aryl Aldehydes
Organic Letters2001Vol. 3(17), pp. 2733–2735
Citations Over TimeTop 10% of 2001 papers
Daxue Liu, Licheng Zhang, Quan Wang, Chao‐Shan Da, Zhuo‐qun Xin, Rui Wang, Michael C. K. Choi, Albert S. C. Chan
Abstract
[reaction: see text]. Optically active aminonaphthol 3 obtained by condensation of 2-naphthol, benzaldehyde, and (S)-methylbenzylamine followed by N-methylation was found to catalyze the enantioselective ethylation of aryl aldehydes to secondary alcohols with high enantioselectivities (up to 99.8%) at room temperature.
Related Papers
- → Synthesis of new chiral catalysts, pyridyl- and bipyridylalcohols, for the enantioselective addition of diethylzinc to benzaldehyde(1998)38 cited
- → Chiral o-hydroxyarylphosphine oxides: a new family of efficient catalysts in asymmetric addition of diethylzinc to benzaldehyde(1998)29 cited
- Asymmetric Amplifying Phenomena in Enantioselective Addition of Diethylzinc to Benzaldehyde(1989)
- → Synthesis of C2-symmetrical 1,1′-disubstituted ferrocenyl amino alcohols and use in catalytic asymmetric addition of diethylzinc to benzaldehyde(1999)23 cited
- → Catalytic Activity of Isoborneol-Derived Sulfides in Asymmetric Addition of Diethylzinc to Benzaldehyde.(1995)14 cited