From Macrocycle Dipeptide Lactams To Azabicyclo[X.Y.0]alkanone Amino Acids: A Transannular Cyclization Route for Peptide Mimic Synthesis
Organic Letters2006Vol. 8(13), pp. 2851–2854
Citations Over Time
Abstract
[reaction: see text] Macrocyclic and fused bicyclic dipeptides are complementary motifs for mimicry of different types of beta-turn geometry. Macrocyclic dipeptide mimics have served as precursors for the synthesis of their bicyclic counterparts using electrophilic transannular cyclizations of 9- and 10-membered ring lactams 9-12 to form azabicyclo[4.3.0]- and -[5.3.0]alkanone amino esters 13-16.
Related Papers
- → First Observation of Two Consecutive γ Turns in a Crystalline Linear Dipeptide(2004)53 cited
- → Self-Assembly Dipeptide Hydrogel: The Structures and Properties(2021)45 cited
- → β-Turn structure in glycinylphenylalanine dipeptide based N-amidothioureas(2013)29 cited
- → Solid-Phase Syntheses of Nω-Propylarginine-Containing Dipeptides, Dipeptide Esters, and Dipeptide Amides(1999)7 cited
- Developments of the coordination mode,structure and stabilization of copper(II)-dipeptide complexes(2006)