New Synthesis of 1-Substituted-1H-indazoles via 1,3-Dipolar Cycloaddition of in situ Generated Nitrile Imines and Benzyne
Organic Letters2010Vol. 12(15), pp. 3368–3371
Citations Over TimeTop 10% of 2010 papers
Abstract
A new synthesis of 1-substitued-1H-indazoles via 1,3-dipolar cycloaddition of nitrile imines to benzyne is described. The reaction is completed within 5 min, affording the corresponding N(1)−C(3) disubstituted indazoles in moderate to excellent yields.
Related Papers
- → A Photoinduced, Benzyne Click Reaction(2014)66 cited
- → Aryne cycloaddition with 3-oxidopyridinium species(2012)33 cited
- → Cycloaddition reactions of benzyne with olefins(2014)23 cited
- → Double [3 + 2] cycloaddition of nitrile oxides with allenoates: Synthesis of spirobidihydroisoxazoles(2018)15 cited
- → Cycloaddition of nitrile oxides to homochiral vinyl ethers(1994)25 cited