Direct Synthesis of Chiral Tertiary Diphosphines via Pd(II)-Catalyzed Asymmetric Hydrophosphination of Dienones
Organic Letters2011Vol. 13(21), pp. 5862–5865
Citations Over TimeTop 10% of 2011 papers
Abstract
A highly diastereo- and enantioselective Pd(II)-catalyzed hydrophosphination of dienones with Ph(2)PH involving formation of double C*-P bonds has been developed, providing a series of chiral tertiary diphosphines (chiral PCP pincer ligands) in high yields. A catalytic cycle for the reaction was proposed.
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