Diastereoselective Palladium-Catalyzed α-Arylation of 4-Substituted Cyclohexyl Esters
Organic Letters2008Vol. 10(22), pp. 5251–5254
Citations Over TimeTop 18% of 2008 papers
Abstract
A diastereoselective palladium-catalyzed arylation of 4-substituted cyclohexyl esters has been developed. The reaction proceeds at room temperature in the presence of [(t-Bu3P)PdBr]2 providing products in up to 37:1 dr.
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