The structure based design of dual HDAC/BET inhibitors as novel epigenetic probes
MedChemComm2014Vol. 5(3), pp. 342–351
Citations Over TimeTop 11% of 2014 papers
Stephen J. Atkinson, Peter E. Soden, Davina C. Angell, Marcus Bantscheff, Chun‐wa Chung, Kathryn A. Giblin, Nicholas Smithers, Rebecca C. Furze, Laurie Gordon, Gerard Drewes, Inmaculada Rioja, Jason Witherington, Nigel J. Parr, Rab K. Prinjha
Abstract
DUAL946 (1) inhibits BET and HDAC proteins in chemoproteomic cell lysate experiments and in immune and cancer cells.
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