Relationship between ketogenesis and gluconeogenesis in isolated hepatocytes from newborn rats
Biochemical Journal1981Vol. 200(2), pp. 429–433
Citations Over TimeTop 12% of 1981 papers
Abstract
In hepatocytes from 1-day-old rats, active gluconeogenesis occurs in parallel with active ketogenesis, although the carbon atoms of non-esterified fatty acids do not participate in glucose synthesis. Once a significant ketogenesis is established, a further increase does not enhance gluconeogenesis. Indeed, octanoate is more ketogenic than oleate, but stimulates gluconeogenesis to a similar extent.
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