Ether Aryl Sulfonic Acid Esters with Improved Antimalarial/Anticancer Activities
Australian Journal of Chemistry2006Vol. 59(4), pp. 277–282
Citations Over TimeTop 19% of 2006 papers
Abstract
Our previous report showed that our current benchmark agent, 4-methoxyphenyl p-toluenesulfonate, is a selective antimalarial/anticancer agent. A series of related sulfones and sulfonic acid esters is now examined. 4-Allyloxyphenyl p-toluenesulfonate is a superior antimalarial/anticancer agent. 4-Methoxyphenyl 4-nitrobenzenesulfonate is a superior antimalarial agent, but shows poorer inhibition of human skin cancer cells.
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