Transcriptional signatures of Mycobacterium tuberculosis in mouse model of intraocular tuberculosis
Pathogens and Disease2019Vol. 77(5)
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Sudhanshu Abhishek, Michelle B. Ryndak, Alpa Choudhary, Sumedha Sharma, Amod Gupta, Vishali Gupta, Nirbhai Singh, Suman Laal, Indu Verma
Abstract
Differentially expressed mycobacterial genes identified in an intravenously challenged paucibacillary mouse IOTB model and presence of these transcripts in human IOTB samples highlight the possible role of these genes for survival of M. tuberculosis in the ocular environment, thus contributing to pathogenesis of IOTB.
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