Evaluation of wild-type MIC distributions as a tool for determination of clinical breakpoints for Mycobacterium tuberculosis
Journal of Antimicrobial Chemotherapy2009Vol. 64(4), pp. 786–793
Citations Over TimeTop 12% of 2009 papers
Thomas Schön, Pontus Juréen, Christian G. Giske, Erja Chryssanthou, Erik Sturegård, Jim Werngren, Gunnar Kahlmeter, Sven Hoffner, Kristian Ängeby
Abstract
Utilizing the wild-type MIC distribution was found to be as useful in M. tuberculosis as in other bacteria when setting clinical breakpoints. We suggest that the present clinical breakpoints should be re-evaluated, taking into account wild-type MIC distributions and available pharmacokinetic data.
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