Pharmacokinetics of ertapenem in outpatients with complicated urinary tract infections
Journal of Antimicrobial Chemotherapy2014Vol. 69(9), pp. 2517–2521
Citations Over TimeTop 19% of 2014 papers
Jian Zhou, Zuraidah Sulaiman, Ryan Llorin, Kim‐Hor Hee, Lawrence Soon-U Lee, David Chien Lye, Dale Fisher, Vincent H. Tam
Abstract
The pharmacokinetics of ertapenem in serum and urine were characterized. Our simulations suggested that a sufficiently high ertapenem concentration could be achieved in urine to overcome low to intermediate resistance. Clinical investigations to validate our findings are warranted.
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