The Fate of Trimethylamine Oxide and Trimethylamine in Man

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Abstract

Normal human urine contains small amounts of trimethylamine oxide but no appreciable trimethylamine. Trimethylamine when administered orally appears mainly as trimethylamine oxide in the urine; trimethylamine oxide similarly administered is excreted unchanged, thus proving the existence in man of a system capable of oxidizing trimethylamine.

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