Review on green chemistry Suzuki cross coupling in aqueous media
Canadian Journal of Chemistry2005Vol. 83(3), pp. 266–272
Citations Over TimeTop 10% of 2005 papers
Abstract
The Suzuki cross-coupling reaction is a very efficient, reliable, and environmentally friendly method for the introduction of novel carboncarbon bonds into molecules. This review summarizes recent advances in the use of the reaction in aqueous media with a focus on different types of ligands and the ligandless protocols currently in use. Several synthetic targets for the reaction have been mentioned. The work summarizes recent results from studies on asymmetric Suzuki reactions performed in organic aqueous mixed solvents.Key words: Suzuki reaction, green chemistry, metal-catalyzed cross-coupling reactions, aqueous synthesis media.
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