Lipid Rafts, Detergent-Resistant Membranes, and Raft Targeting Signals
Physiology2006Vol. 21(6), pp. 430–439
Citations Over TimeTop 1% of 2006 papers
Abstract
Lipid rafts are liquid-ordered (l(o)) phase microdomains proposed to exist in biological membranes. Rafts have been widely studied by isolating l(o)-phase detergent-resistant membranes (DRMs) from cells. Recent findings have shown that DRMs are not the same as preexisting rafts, prompting a major revision of the raft model. Nevertheless, raft-targeting signals identified by DRM analysis are often required for protein function, implicating rafts in a variety of cell processes.
Related Papers
- → Lipid Rafts, Detergent-Resistant Membranes, and Raft Targeting Signals(2006)463 cited
- → Involvement of lipid microdomains in human endothelial cells infected by Streptococcus agalactiae type III belonging to the hypervirulent ST-17(2020)6 cited
- → Membrane Microdomain Signaling: Lipid Rafts in Biology and Medicine(2004)35 cited
- → Reversible Dissolution of Microdomains in Detergent-Resistant Membranes at Physiological Temperature(2015)2 cited
- → Cell-Free Antibody Capture Method for Analysis of Detergent-Resistant Membrane Rafts(2008)2 cited