Restricting Excessive Cardiac Action Potential and QT Prolongation
Circulation2005Vol. 112(10), pp. 1392–1399
Citations Over TimeTop 1% of 2005 papers
Norbert Jost, László Virág, Miklós Bitay, J. Takács, Csaba Lengyel, Péter Biliczki, Z.P. Nagy, Gábor Bogáts, David A. Lathrop, Julius Gy. Papp, András Varró
Abstract
Pharmacological IKs block in the absence of sympathetic stimulation plays little role in increasing normal human ventricular muscle APD. However, when human ventricular muscle repolarization reserve is attenuated, IKs plays an increasingly important role in limiting action potential prolongation.
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