In Vitro and In Vivo Characterization of Pigment Epithelial Cells Differentiated from Primate Embryonic Stem Cells
Investigative Ophthalmology & Visual Science2004Vol. 45(3), pp. 1020–1020
Citations Over TimeTop 10% of 2004 papers
Masatoshi Haruta, Yoshiki Sasai, Hiroshi Kawasaki, Kaori Amemiya, Sotaro Ooto, Masaaki Kitada, Hirofumi Suemori, Norio Nakatsuji, Chizuka Idé, Yoshihito Honda, Masayo Takahashi
Abstract
The ESPEs had morphologic and physiological properties of normal RPE cells, and these findings suggest that these cells may provide an unlimited source of primate cells to be used for the study of pathogenesis, drug development, and cell-replacement therapy in eyes with retinal degenerative diseases due to primary RPE dysfunction.
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