Mitochondrial Abnormalities in Patients with LHON-like Optic Neuropathies
Investigative Ophthalmology & Visual Science2006Vol. 47(10), pp. 4211–4211
Citations Over TimeTop 13% of 2006 papers
Abstract
Primary LHON mutations are less common in patients with LHON-like optic neuropathy selected from a clinical setting than in patients with LHON from multigenerational families. The results suggest that mitochondrial dysfunction plays a role in this type of optic neuropathy whether or not primary LHON mutations are present. This information has implications for diagnostic testing and for future investigations into mechanisms of disease.
Related Papers
- → Mitochondrial Abnormalities in Patients with LHON-like Optic Neuropathies(2006)104 cited
- → Leber’s hereditary optic neuropathy and vitamin B12 deficiency(2006)34 cited
- Mutations for Leber hereditary optic neuropathy in patients with alcohol and tobacco optic neuropathy.(2011)
- Clinical spectrum of Leber's hereditary optic neuropathy.(1997)
- → A Case of a 23-Year-Old Male With Leber Hereditary Optic Neuropathy With a Rare Mutation(2022)