Functions of the Type 1 BMP Receptor Acvr1 (Alk2) in Lens Development: Cell Proliferation, Terminal Differentiation, and Survival
Investigative Ophthalmology & Visual Science2008Vol. 49(11), pp. 4953–4953
Citations Over TimeTop 10% of 2008 papers
Ramya Rajagopal, Lisa K. Dattilo, Vesa Kaartinen, Chu‐Xia Deng, Lieve Umans, An Zwijsen, Anita B. Roberts, Erwin P. Böttinger, David C. Beebe
Abstract
This study revealed a novel switch in the functions of Acvr1 in regulating lens cell proliferation. Previously unknown functions mediated by this receptor included regionalization of the lens epithelium and cell cycle exit during fiber cell differentiation.
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