The balance of expression of PTPN22 splice forms is significantly different in rheumatoid arthritis patients compared with controls
Genome Medicine2012Vol. 4(1), pp. 2–2
Citations Over TimeTop 13% of 2012 papers
Marcus Ronninger, Yongjing Guo, Klementy Shchetynsky, Andrew Hill, Mohsen Khademi, Tomas Olsson, Padmalatha S. Reddy, Maria Seddighzadeh, James D. Clark, Lih-Ling Lin, Margot O’Toole, Leonid Padyukov
Abstract
Our data show that RA patients and healthy controls have a shift in balance of expression of splice forms derived from the PTPN22 gene. This balance seems not to be caused by treatment and may be of importance during immune response due to great structural differences in the encoded PTPN22 proteins.
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