Resveratrol prevents sarcopenic obesity by reversing mitochondrial dysfunction and oxidative stress via the PKA/LKB1/AMPK pathway
Aging2019Vol. 11(8), pp. 2217–2240
Citations Over TimeTop 10% of 2019 papers
Yujie Huang, Xiaohui Zhu, Ka Chen, Hedong Lang, Yong Zhang, Pengfei Hou, Li Ran, Min Zhou, Jiawei Zheng, Long Yi, Mantian Mi, Qianyong Zhang
Abstract
Resveratrol prevented high-fat diet-induced muscle atrophy in aged rats by reversing mitochondrial dysfunction and oxidative stress, which was partially mediated by the PKA/LKB1/AMPK pathway. These findings indicate that resveratrol might have potential uses for the prevention and treatment of sarcopenic obesity.
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