PRCC/TFE3 Fusion Gene
Definitions2020
National Cancer Institute
Abstract
A fusion gene that results from a chromosomal translocation t(X;1)(p11.2;q21.2) which fuses the 5' half of the PRCC gene to exon 2 of the TFE3 gene. This rearrangement is associated with papillary renal cell carcinoma.
Related Papers
- → RNA sequencing of Xp11 translocation-associated cancers reveals novel gene fusions and distinctive clinicopathologic correlations(2018)96 cited
- → Xp11.2 translocation renal cell carcinoma with NONO-TFE3 gene fusion: morphology, prognosis, and potential pitfall in detecting TFE3 gene rearrangement(2016)72 cited
- → Novel gene fusion of PRCC–MITF defines a new member of MiT family translocation renal cell carcinoma: clinicopathological analysis and detection of the gene fusion by RNA sequencing and FISH(2017)33 cited
- → Xp11.2 Translocation Renal Cell Carcinoma With TFE3 Rearrangement: Distinct Morphological Features and Prognosis With Different Fusion Partners(2021)18 cited
- → PRCC/TFE3 Fusion Gene(2020)