Hydrogel-Based Drug Delivery Systems for Poorly Water-Soluble Drugs
Citations Over TimeTop 10% of 2015 papers
Abstract
Hydrogels are three-dimensional materials that can withstand a great amount of water incorporation while maintaining integrity. This allows hydrogels to be very unique biomedical materials, especially for drug delivery. Much effort has been made to incorporate hydrophilic molecules in hydrogels in the field of drug delivery, while loading of hydrophobic drugs has not been vastly studied. However, in recent years, research has also been conducted on incorporating hydrophobic molecules within hydrogel matrices for achieving a steady release of drugs to treat various ailments. Here, we summarize the types of hydrogels used as drug delivery vehicles, various methods to incorporate hydrophobic molecules in hydrogel matrices, and the potential therapeutic applications of hydrogels in cancer.
Related Papers
- → Hydrogels for Hydrophobic Drug Delivery. Classification, Synthesis and Applications(2018)289 cited
- → Hydrogel-Based Drug Delivery Systems for Poorly Water-Soluble Drugs(2015)204 cited
- → Environment sensitive hydrogels for drug delivery applications(2019)158 cited
- → Injectable microgel–hydrogel composites “plum pudding gels”: new system for prolonged drug delivery(2019)17 cited
- → Crosslinked natural hydrogels for drug delivery systems(2022)6 cited