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Antagonistic drug combinations that select against drug resistance: From bacteria to cancer
Cancer Biology & Therapy2007Vol. 6(7), pp. 1013–1014
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Abstract
Any drug selects for drug resistance. But super-antagonistic drug combinations can select for drug sensitivity. This has important application not only for antibacterial therapy but also for cancer therapy: to control cancer with lesser side effects and to eliminate drug-resistant cancer cells, while sparing sensitive normal cells.
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