P27-PPE36 (Rv2108) Mycobacterium tuberculosis Antigen – Member of PPE Protein Family with Surface Localization and Immunological Activities

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Abstract

Mycobacterium Tuberculosis Pathogenicity 540 PPE36 protein genetically fused into the flagellin. We found that P27-PPE36 expressed into the flagellin led to the strongest cellular responses, where we obtained the highest production of IFN- and cell proliferation, an indication of specific Th1-like orientation of the immune response.

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