Carl Poisson
Vertex Pharmaceuticals (Canada)(CA)
Publications by Year
Research Areas
Hepatitis C virus research, HIV/AIDS drug development and treatment, Hepatitis B Virus Studies, Biochemical and Molecular Research, Crystallization and Solubility Studies
Most-Cited Works
- → Discovery of thiophene-2-carboxylic acids as potent inhibitors of HCV NS5B polymerase and HCV subgenomic RNA replication. Part 2: Tertiary amides(2004)101 cited
- → Discovery of thiophene-2-carboxylic acids as potent inhibitors of HCV NS5B polymerase and HCV subgenomic RNA replication. Part 1: Sulfonamides(2004)76 cited
- → Identification of N,N-Disubstituted Phenylalanines as a Novel Class of Inhibitors of Hepatitis C NS5B Polymerase(2003)68 cited
- → Further SAR studies on novel small molecule inhibitors of the hepatitis C (HCV) NS5B polymerase(2003)18 cited
- → Synthesis and evaluation of NS5A inhibitors containing diverse heteroaromatic cores(2014)13 cited
- → Discovery of Novel Thiophene-Based, Thumb Pocket 2 Allosteric Inhibitors of the Hepatitis C NS5B Polymerase with Improved Potency and Physicochemical Profiles(2016)12 cited
- → HCV NS5B polymerase-bound conformation of a soluble sulfonamide inhibitor by 2D transferred NOESY(2004)12 cited
- → Benzimidazole-containing HCV NS5A inhibitors: Effect of 4-substituted pyrrolidines in balancing genotype 1a and 1b potency(2014)8 cited
- → Preparation of 2-alkenylperhydro-1,3-benzoxazines and application for 2-isoxazolines synthesis(2009)1 cited
- → CCDC 707016: Experimental Crystal Structure Determination(2010)