Jessica Orf
Gilead Sciences (United States)(US)
Publications by Year
Research Areas
Immune cells in cancer, Cancer Mechanisms and Therapy, Epigenetics and DNA Methylation, Acute Myeloid Leukemia Research, Advanced Breast Cancer Therapies
Most-Cited Works
- → Single-Cell Analyses Inform Mechanisms of Myeloid-Targeted Therapies in Colon Cancer(2020)1,571 cited
- → Cabozantinib (XL184), a Novel MET and VEGFR2 Inhibitor, Simultaneously Suppresses Metastasis, Angiogenesis, and Tumor Growth(2011)1,303 cited
- → Metastatic properties and genomic amplification of the tyrosine kinase gene ACK1(2005)145 cited
- → Activity of tumor-associated macrophage depletion by CSF1R blockade is highly dependent on the tumor model and timing of treatment(2021)54 cited
- → Preclinical Evaluation of AMG 925, a FLT3/CDK4 Dual Kinase Inhibitor for Treating Acute Myeloid Leukemia(2014)34 cited
- → Addressing PXR liabilities of phthalazine-based hedgehog/smoothened antagonists using novel pyridopyridazines(2010)32 cited
- → Design of 1-piperazinyl-4-arylphthalazines as potent Smoothened antagonists(2010)21 cited
- → The optimization of aminooxadiazoles as orally active inhibitors of Cdc7(2013)21 cited
- → Discovery of amide replacements that improve activity and metabolic stability of a bis-amide smoothened antagonist hit(2011)21 cited
- → Brief report: STING expressed in tumor and non-tumor compartments has distinct roles in regulating anti-tumor immunity(2022)19 cited