Stephen C. Yabut
Johnson & Johnson (United States)(US)Janssen (United States)(US)
Publications by Year
Research Areas
Chemical Synthesis and Analysis, Blood Coagulation and Thrombosis Mechanisms, Click Chemistry and Applications, Synthesis and Biological Evaluation, Metabolism, Diabetes, and Cancer
Most-Cited Works
- → Potent, Small-Molecule Inhibitors of Human Mast Cell Tryptase. Antiasthmatic Action of a Dipeptide-Based Transition-State Analogue Containing a Benzothiazole Ketone(2003)82 cited
- → Potent, Orally Active GPIIb/IIIa Antagonists Containing a Nipecotic Acid Subunit. Structure−Activity Studies Leading to the Discovery of RWJ-53308(1999)71 cited
- → In-Depth Study of Tripeptide-Based α-Ketoheterocycles as Inhibitors of Thrombin. Effective Utilization of the S1‘ Subsite and Its Implications to Structure-Based Drug Design(2004)67 cited
- → Potent Thrombin Inhibitors That Probe the S1‘ Subsite: Tripeptide Transition State Analogues Based on a Heterocycle-Activated Carbonyl Group(1996)65 cited
- → Potent, nonpeptide inhibitors of human mast cell tryptase. Synthesis and biological evaluation of novel spirocyclic piperidine amide derivatives(2008)53 cited
- → Solid-phase synthesis via N-terminal attachment to the 2-chlorotrityl resin(1997)46 cited
- → Inhibitors of Ketohexokinase: Discovery of Pyrimidinopyrimidines with Specific Substitution that Complements the ATP-Binding Site(2011)40 cited
- → Solid-phase parallel synthesis applied to lead optimization: Discovery of potent analogues of the GPIIb/IIIa antagonist RWJ-50042(1996)32 cited
- → Exploration of Potential Prodrugs of RWJ‐445167, an Oxyguanidine‐based Dual Inhibitor of Thrombin and Factor Xa(2006)25 cited
- → Pyrimidinopyrimidine inhibitors of ketohexokinase: Exploring the ring C2 group that interacts with Asp-27B in the ligand binding pocket(2012)16 cited