Michael Melnick
BioAtla (United States)(US)
Publications by Year
Research Areas
HIV/AIDS drug development and treatment, Chemical Synthesis and Analysis, Carbohydrate Chemistry and Synthesis, Enzyme Structure and Function, Quinazolinone synthesis and applications
Most-Cited Works
- → Potent Inhibitors of LpxC for the Treatment of Gram-Negative Infections(2011)97 cited
- → The Structure of the Carboxyltransferase Component of Acetyl-CoA Carboxylase Reveals a Zinc-Binding Motif Unique to the Bacterial Enzyme,(2006)87 cited
- → Protein structure-based design of potent orally bioavailable, nonpeptide inhibitors of human immunodeficiency virus protease.(1995)51 cited
- → Structure of a small‐molecule inhibitor complexed with GlmU from Haemophilus influenzae reveals an allosteric binding site(2008)50 cited
- → Characterization of substrate binding and catalysis in the potential antibacterial target N‐acetylglucosamine‐1‐phosphate uridyltransferase (GlmU)(2007)43 cited
- → Structure-Based Design and Synthesis of Substituted 2-Butanols as Nonpeptidic Inhibitors of HIV Protease: Secondary Amide Series(1996)43 cited
- → The Use of Biochemical and Biophysical Tools for Triage of High‐Throughput Screening Hits – A Case Study with Escherichia coli Phosphopantetheine Adenylyltransferase(2010)32 cited
- → Bis Tertiary Amide Inhibitors of the HIV-1 Protease Generated via Protein Structure-Based Iterative Design(1996)30 cited
- → A phase 1/2 dose-escalation and expansion study of a conditionally active anti-AXL humanized monoclonal antibody (BA3011) in patients with advanced solid tumors.(2018)14 cited
- → ChemInform Abstract: Structure‐Based Design and Synthesis of Substituted 2‐Butanols as Nonpeptidic Inhibitors of HIV Protease: Secondary Amide Series.(1996)1 cited