Brian R. Hearn
Olema Pharmaceuticals (United States)(US)
Publications by Year
Research Areas
Synthetic Organic Chemistry Methods, Endoplasmic Reticulum Stress and Disease, Ubiquitin and proteasome pathways, CRISPR and Genetic Engineering, Asymmetric Synthesis and Catalysis
Most-Cited Works
- → Pharmacological brake-release of mRNA translation enhances cognitive memory(2013)729 cited
- → USP7 small-molecule inhibitors interfere with ubiquitin binding(2017)334 cited
- → Pharmacological dimerization and activation of the exchange factor eIF2B antagonizes the integrated stress response(2015)260 cited
- → Ceapins are a new class of unfolded protein response inhibitors, selectively targeting the ATF6α branch(2016)199 cited
- → Predicting and Improving the Membrane Permeability of Peptidic Small Molecules(2012)111 cited
- → Delivery of antimicrobials into parasites(2003)73 cited
- → Biodegradable Tetra-PEG Hydrogels as Carriers for a Releasable Drug Delivery System(2015)70 cited
- → A Divergent Approach to the Myriaporones and Tedanolide: Completion of the Carbon Skeleton of Myriaporone 1(2002)53 cited
- → A divergent approach to the myriaporones and tedanolide: Enantioselective preparation of the common intermediate(1998)45 cited
- → PET Imaging of the EPR Effect in Tumor Xenografts Using Small 15 nm Diameter Polyethylene Glycols Labeled with Zirconium-89(2019)43 cited